EOLO.
Redefining Gastrointestinal Diagnostics
Get the highlights.
CliniChrom has developed an instrument that fully automates all pre-analytical
treatment steps, sample injection, and analysis.
It processes over 1,440 tubes per day—equivalent to approximately 180 patients
per day—significantly boosting operational efficiency.
In less than a minute, EOLO delivers concentration levels of hydrogen, methane and carbon dioxide (control analyte), with the option to additionally measure hydrogen sulfide.
Results can be printed, exported as CSV files, or transmitted directly to a
Laboratory Information Management System (LIMS).
The system is fully customizable to meet your specific requirements,
further optimizing laboratory workflows and productivity.
This approach ensures maximum resource utilization, reduced turnaround times, and a significant improvement in both the efficiency and accuracy of analytical results.
CliniChrom has developed an instrument that fully automates all pre-analytical
treatment steps, sample injection, and analysis.
It processes over 1,440 tubes per day—equivalent to approximately 180 patients
per day—significantly boosting operational efficiency.
In less than a minute, EOLO delivers concentration levels of hydrogen, methane and carbon dioxide (control analyte), with the option to additionally measure hydrogen sulfide.
Results can be printed, exported as CSV files, or transmitted directly to a
Laboratory Information Management System (LIMS).
The system is fully customizable to meet your specific requirements,
further optimizing laboratory workflows and productivity.
This approach ensures maximum resource utilization, reduced turnaround times, and a significant improvement in both the efficiency and accuracy of analytical results.

EOLO - The revolutionary all-in-one analyzer for Carbohydrate Intolerances, SIBO and H. pylori
EOLO by CLINICHROM is a fully automated, integrated platform for diagnosing carbohydrate intolerances, SIBO, and H. pylori infections.
This state-of-the-art system streamlines laboratory workflows—from sample injection to LIMS reporting—by analyzing breath samples collected after the ingestion of specific sugar substrates or a ¹³C-labeled urea solution.
It provides clinical laboratories with a highly efficient and powerful tool for the diagnosis of digestive disorders.
Why does a patient need a breath test ?
Breath tests are used to evaluate how effectively the body digests and absorbs certain sugars. Some individuals have difficulty absorbing carbohydrates such as lactose or fructose. When this occurs, undigested sugars are fermented by gut bacteria, producing gases like hydrogen, methane and hydrogen sulfide, which are then detected in exhaled breath.
Elevated gas levels indicate carbohydrate malabsorption, bacterial overgrowth or bacterial infection, supporting the diagnosis of gastrointestinal conditions such as lactose intolerance, fructose malabsorption, small intestinal bacterial overgrowth (SIBO) or H. pylori infection.
Breath testing is commonly used to diagnose:
- Carbohydrate Intolerance / Malabsortion
- Lactose intolerance
- Fructose malabsortion
- Sorbitol malabsortion
- Laculose malabsortion
- SIBO (Small Intestinal Bacterial Overgrowth)
- Helicobacter pylori infection.
What does the test involve ?
1. Preparación
Se requiere cierta preparación antes de la prueba. Esta preparación implica suspender ciertos medicamentos y estar en ayunas. Antes de tomar la muestra, el paciente debe beber una solución rica en azúcar.
1. Preparation
Some preparation is required before the test. This preparation involves discontinuing certain medications and fasting. Prior to taking the sample, the patient must drink a high-sugar solution.
2. Digestión
Si una persona tiene intolerancia al azúcar, este no se absorbe por completo en el intestino delgado y pasa al intestino grueso. Allí, las bacterias intestinales lo fermentan, lo que provoca una mayor producción de gases como hidrógeno, metano y, a veces, sulfuro de hidrógeno.
2. Digestion
If a person has a sugar intolerance, the sugar isn't fully absorbed in the small intestine and passes into the large intestine. There, gut bacteria ferment it, leading to increased production of gases like hydrogen, methane, and sometimes hydrogen sulfide.
3. Toma de muestras
Después de beber la solución, el paciente exhala en un tubo utilizando una pajita para medir los niveles de gas. Este proceso debe repetirse a intervalos regulares durante las siguientes tres horas para controlar los cambios en la producción de gases.
3. Sampling
After drinking the solution, the patient exhales into a tube using a straw to measure gas levels. This process must be repeated at regular intervals over the next three hours to monitor changes in gas production.
4. Análisis
El técnico de laboratorio simplemente lee los códigos de barras 1D/2D, carga los tubos etiquetados en el carrusel e inicia la secuencia. El robot inyecta la muestra en el MicroGC, que reporta los niveles de hidrógeno, metano y dióxido de carbono en menos de 2 minutos.
4. Analysis
The lab technician simply reads the 1D/2D barcodes, loads the labeled tubes into the carousel and starts the sequence. The robot injects the sample into the MicroGC, which reports hydrogen, methane, and carbon dioxide levels in under 2 minutes.
1. Preparación
Se requiere cierta preparación antes de la prueba. Esta preparación implica suspender ciertos medicamentos y estar en ayunas. Antes de tomar la muestra, el paciente debe beber una solución rica en azúcar.
1. Preparation
Some preparation is required before the test. This preparation involves discontinuing certain medications and fasting. Prior to taking the sample, the patient must drink a high-sugar solution.
2. Digestión
Si una persona tiene intolerancia al azúcar, este no se absorbe por completo en el intestino delgado y pasa al intestino grueso. Allí, las bacterias intestinales lo fermentan, lo que provoca una mayor producción de gases como hidrógeno, metano y, a veces, sulfuro de hidrógeno.
2. Digestion
If a person has a sugar intolerance, the sugar isn't fully absorbed in the small intestine and passes into the large intestine. There, gut bacteria ferment it, leading to increased production of gases like hydrogen, methane, and sometimes hydrogen sulfide.
3. Toma de muestras
Después de beber la solución, el paciente exhala en un tubo utilizando una pajita para medir los niveles de gas. Este proceso debe repetirse a intervalos regulares durante las siguientes tres horas para controlar los cambios en la producción de gases.
3. Sampling
After drinking the solution, the patient exhales into a tube using a straw to measure gas levels. This process must be repeated at regular intervals over the next three hours to monitor changes in gas production.
4. Análisis
El técnico de laboratorio simplemente lee los códigos de barras 1D/2D, carga los tubos etiquetados en el carrusel e inicia la secuencia. El robot inyecta la muestra en el MicroGC, que reporta los niveles de hidrógeno, metano y dióxido de carbono en menos de 2 minutos.
4. Analysis
The lab technician simply reads the 1D/2D barcodes, loads the labeled tubes into the carousel and starts the sequence. The robot injects the sample into the MicroGC, which reports hydrogen, methane, and carbon dioxide levels in under 2 minutes.
Don't miss a thing with H₂S detection.
By incorporating hydrogen sulfide (H₂S) analysis, EOLO detects alternative fermentation pathways missed by standard hydrogen and methane breath analyzers.
This is crucial for low-hydrogen producers, where sulfate-reducing bacteria rapidly convert hydrogen into H₂S, a process that otherwise leads to false negatives.
Consequently, measuring H₂S significantly enhances diagnostic sensitivity for SIBO and carbohydrate malabsorption. By delivering a comprehensive profile of intestinal gases, EOLO reduces diagnostic uncertainty and provides healthcare professionals with robust, high-throughput, and precise results for gastrointestinal disorders.

The most accurate non-invasive diagnostic method for Heliobacter pylori.
Helicobacter pylori is a bacterium associated with gastritis, peptic ulcers and gastric cancer
The EOLO system is capable of performing the ¹³C urea breath test (¹³C-UBT) for the detection of Helicobacter pylori.
In this test, the patient ingests a urea solution labeled with ¹³C. If H. pylori is present, the bacterium metabolizes the urea, producing labeled ¹³CO₂, which is subsequently detected in the exhaled breath.
The analysis is based on the ¹³C/¹²C isotopic ratio, measured by mass spectrometry. This method is non-invasive, fast, and highly accurate, eliminating the need for an endoscopy.
The H. pylori urea breath test is the most accurate non-invasive diagnostic method.

EOLO Advantages.
Discover what makes EOLO unique
Flujo de Trabajo Totalmente Automatizado
EOLO optimiza los flujos de trabajo del laboratorio minimizando la intervención manual y ofreciendo la máxima flexibilidad en la carga de muestras. Además, los procedimientos de calibración y verificación del sistema están totalmente automatizados mediante software.
Fully Automated Workflow
EOLO optimizes laboratory workflows by minimizing manual intervention and offering maximum flexibility in sample loading. Additionally, system calibration and verification procedures are fully automated through software.
Flexibilidad de Capacidad y Rendimiento
Este sistema altamente configurable admite de 360 a 936 tubos de muestras de aliento y analiza cada muestra en menos de un minuto, procesando hasta 180 pacientes diarios con una configuración de doble analizador.
Capacity and Performance Flexibility
This highly configurable system accommodates 360 to 936 breath sampling tubes and analyzes each sample in under a minute, processing up to 180 patients daily with a dual-analyzer configuration.
Alta Resolución y Precisión Analítica
EOLO garantiza diagnósticos clínicos exactos al proporcionar resultados altamente fiables, precisos y reproducibles con un coeficiente de correlación excepcional (R² > 0.999) en todo su rango de calibración. Además, el sistema logra una excelente precisión analítica al demostrar una de las desviaciones estándar relativas más bajas del mercado, con un RSD < 2.5% para H₂, CH₄, CO₂ y H₂S.
High Resolution and Analytical Precision
EOLO ensures accurate clinical diagnoses by delivering highly reliable, precise, and reproducible results with an exceptional correlation coefficient (R² > 0.999) across its entire calibration range. Additionally, the system achieves excellent analytical precision by demonstrating one of the lowest relative standard deviations on the market, with an RSD < 2.5% for H₂, CH₄, CO₂, and H₂S.
Opciones Comerciales Adaptadas a sus Necesidades
Ofrecemos planes de financiación flexibles, incluidos modelos de arrendamiento financiero o de alquiler con opción a compra, junto con opciones de precio por prueba para adaptarse mejor a su presupuesto y flujo de trabajo. Además, disponemos de accesorios completos, kits de muestreo y tubos de aliento.
Commercial Options Tailored to Your Needs
We offer flexible financing plans, including leasing or rent-to-own models, alongside per-test pricing options to best suit your budget and workflow. Additionally, complete accessories, sampling kits, and breath tubes are readily available.
Flujo de Trabajo Totalmente Automatizado
EOLO optimiza los flujos de trabajo del laboratorio minimizando la intervención manual y ofreciendo la máxima flexibilidad en la carga de muestras. Además, los procedimientos de calibración y verificación del sistema están totalmente automatizados mediante software.
Fully Automated Workflow
EOLO optimizes laboratory workflows by minimizing manual intervention and offering maximum flexibility in sample loading. Additionally, system calibration and verification procedures are fully automated through software.
Flexibilidad de Capacidad y Rendimiento
Este sistema altamente configurable admite de 360 a 936 tubos de muestras de aliento y analiza cada muestra en menos de un minuto, procesando hasta 180 pacientes diarios con una configuración de doble analizador.
Capacity and Performance Flexibility
This highly configurable system accommodates 360 to 936 breath sampling tubes and analyzes each sample in under a minute, processing up to 180 patients daily with a dual-analyzer configuration.
Alta Resolución y Precisión Analítica
EOLO garantiza diagnósticos clínicos exactos al proporcionar resultados altamente fiables, precisos y reproducibles con un coeficiente de correlación excepcional (R² > 0.999) en todo su rango de calibración. Además, el sistema logra una excelente precisión analítica al demostrar una de las desviaciones estándar relativas más bajas del mercado, con un RSD < 2.5% para H₂, CH₄, CO₂ y H₂S.
High Resolution and Analytical Precision
EOLO ensures accurate clinical diagnoses by delivering highly reliable, precise, and reproducible results with an exceptional correlation coefficient (R² > 0.999) across its entire calibration range. Additionally, the system achieves excellent analytical precision by demonstrating one of the lowest relative standard deviations on the market, with an RSD < 2.5% for H₂, CH₄, CO₂, and H₂S.
Opciones Comerciales Adaptadas a sus Necesidades
Ofrecemos planes de financiación flexibles, incluidos modelos de arrendamiento financiero o de alquiler con opción a compra, junto con opciones de precio por prueba para adaptarse mejor a su presupuesto y flujo de trabajo. Además, disponemos de accesorios completos, kits de muestreo y tubos de aliento.
Commercial Options Tailored to Your Needs
We offer flexible financing plans, including leasing or rent-to-own models, alongside per-test pricing options to best suit your budget and workflow. Additionally, complete accessories, sampling kits, and breath tubes are readily available.
Tray capacity ranges from 432 to 936 CLINICHROM tubes.*Image: 936 tubes option
La capacidad de la bandeja varía de 432 a 936 tubos CLINICHROM.
*Imagen: opción de 936 tubos
We offer different types of tubes and different cap colors.
Ofrecemos diferentes tipos de tubos y diferentes colores de tapón.
Choose between EOLO GC (intolerances), EOLO MSD (H. pylori), or both.
Elija entre EOLO GC (intolerancias), EOLO MSD (H. pylori) o ambos.
Tray capacity ranges from 432 to 936 CLINICHROM tubes.*Image: 936 tubes option
La capacidad de la bandeja varía de 432 a 936 tubos CLINICHROM.
*Imagen: opción de 936 tubos
We offer different types of tubes and different cap colors.
Ofrecemos diferentes tipos de tubos y diferentes colores de tapón.
Choose between EOLO GC (intolerances), EOLO MSD (H. pylori), or both.
Elija entre EOLO GC (intolerancias), EOLO MSD (H. pylori) o ambos.
Learn more about EOLO today.
Detection Range
Hydrogen:
5 ppm — 200 ppm
Carbon Dioxide:
1,5% — 7,0 %
Methane:
5 ppm — 50 ppm
Hydrogen Sulfide:
10-1000 ppb
