Antiepileptic Drugs in Plasma / Serum

Antiepileptic drugs (AED) are used for the treatment of epilepsy, a chronic neurological disorder, which is characterised by recurrent epileptic seizures.

Manual Sample Preparation

The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9200) contains all analyte specific components required for the quantification of 27 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9000) contains the components needed for sample preparation and LC-MS/MS analysis. It can be used with all ClinMass® Add-on Sets of the TDM Kit System. The analytical column is suitable for the whole analyte panel (156 compounds).

On-line SPE

The ClinMass® Add-on Set for Antiepileptic Drugs (order no. MS9250) contains all analyte specific components required for the quantification of 26 different AEDs and metabolites. The ClinMass® TDM Platform (order no. MS9050) contains the components needed for on-line SPE LCMS/MS analysis. It can be used with all ClinMass® Add-on Sets of the “TDM Kit System, on-line” (BZP, TCA, …). The analytical column is suitable for the whole analyte panel (153 compounds).

Listado de Analitos:

10-OH Cabamazepine Levetiracetam Retigabine
Carbamazepine N-Desmethylmethsuximide Rufinamide
Carbamazepine-diol Oxcarbazepine Stiripentol
Carbamazepine-epoxide PEMA Sulthiame
Felbamate Perampanel Tiagabine
Ethosuximide Phenorbarbital Topiramate
Gabapentine Phenytoin Valproic Acid
Lacosamide Pregabaline Zonisamide
Lamotrigine Primidone  

 

Disponemos de un manual de usuario para esta aplicación. Puede solicitarlo enviando un correo a clinica@ingenieria-analitica.com

 

Referencia 

Descripción

Cantidad

MS9000

ClinMass® Platforma TDM para 400 análisis

1 pce.

Componentes del kit (Referencia MS9000):

MS9005

Solución de lavado del automuestreador

1000 ml

MS9007

Fase Móvil A

2 x MS9007 (2 x 1000 ml)

MS9008

Fase Móvil B

1000 ml

MS9020

Viales de preparación de muestra

4 x MS9020 (4 x 100 pcs.)

MS9021

Precipitante P

2 x MS9021 (2 x 25 ml)

Start Accessories:

MS9030

Columna Analítica con cromatograma test

1 pce.

MS9032

Pre-filtro

1 pce.

Accessories:

MS9022

Solución de dilución D

50 ml

MS9200

ClinMass® Kit antiepilépticos en Serum / Plasma para 200 análisis

1 pce.

Componentes del kit (Referencia MS9200):

MS9212

Estándar interno IS, liofilizado

5 x 5 ml

MS9213

Calibrador en serum liofilizado (Nivel 0 – 3)

4 x 1 x 1 ml

 

Manual

1 pce.

Accesorios de inicio:

MS9214

Mezcla de optimización liofilizada

5 x 2 ml

ClinChek® Controles:

MS9282

Controles en serum liofilizados Nivel I, II

2 x 5 x 1 ml