Hemoglobin Variants and Beta-Thalassemia Screening

Defects in genes, which are responsible for the synthesis of the hemoglobin molecule, result in a group of hereditary diseases termed as ”hemoglobinopathies”. Depending on the molecular defect, hemoglobinopathies may be classified in ”structural hemoglobin variants” and in ”thalassemias”.

This test kit allows for a reliable separation and identification of the common and clinically significant hemoglobin variants. For beta-thalassemia screening the kit ensures an exact quantification of HbF and HbA2. A ready-to-use test solution (containing HbA1c, HbF, HbA0, HbE, HbA2, HbD, HbS, HbC), a hemolysate calibrator (containing HbF, HbA2) as well as three hemolysate controls are available for quality assurance.